Table 3.

Summary of analysis showing the BPAC for each chemical tested across both cell types. Includes comparison to 2018 ACGIH TLV and reported LOAEL and NOAEL values from in vivo inhalation studies reviewed in the EPA IRIS toxicological reviews for each respective chemical (www.epa.gov/iris). Abbreviations used: N/A: no gene set met criteria to calculate a BPAC, NR: not reported in the literature reference. ‘--’ indicates that the chemical was not tested in pHPEC cells.

Chemical Name	BEAS-2B BPAC (ppm)	pHPEC BPAC (ppm)	Representative LOAEL (ppm)	Representative NOAEL (ppm)	TLV (ppm)
Acrolein	0.586	--	0.25	NR	0.1
1-Bromopropane	2.246	N/A	NR	6040	0.1
Formaldehyde	N/A	--	6	NR	0.3
1,3-Butadiene	13.979	--	200	NR	10
Carbon Tetrachloride	9.563	N/A	20	5	10
Acetaldehyde	N/A	--	400	150	25
Trichloroethylene	44.842	28.148	50	25	50
Dichloromethane	142.127	226.73	8400	4200	100