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. 2022 Aug 16;21(24):2602–2614. doi: 10.1080/15384101.2022.2105885

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Figure 5. — DLGAP1-AS2 targeted c-Myc via YTHDF1-dependent manner. (a) Co-localization analysis using fluorescence in situ hybridization (FISH) displayed the distribution of DLGAP1-AS2, YTHDF1 and c-Myc in A549 cells. (b) IGV viewer showed the m⁶A site in the c-Myc mRNA based on MeRIP-Seq data. (c) GEPIA database demonstrated the positive correlation within c-Myc and DLGAP1-AS2, or c-Myc with YTHDF1 (p < 0.001). (B) TCGA database illustrated the high-expression of c-Myc in LUSC (Lung squamous cell carcinoma, www.tcga.org/).