Table 3.
Univariable association of TP53 status in MOC with clinico-pathological parameters in a survival cohort combining the Genomic Analysis of Mucinous Tumors (GAMuT) and the Ovarian Tumor Tissue Analysis (OTTA) consortium.
| TP53 normal | TP53 abnormal | p-value | |
|---|---|---|---|
| MOC (N) | 165 | 259 | |
| Age, mean (SE) | 51.4 +/− 8.6 | 52.1 +/− 8.6 | p=0.25, t =−1.151 |
| Stage | |||
| I-II | 136 (85.0%) | 222 (89.1%) | p=0.222 |
| III-IV | 24 (15.0%) | 27 (10.8%) | |
| Unknown | 5 | 10 | |
| Grade | |||
| 1 | 66 (44.9%) | 84 (36.8%) | p=0.152 |
| 2 | 66 (44.9%) | 107 (46.9%) | |
| 3 | 15 (10.2%) | 37 (16.2%) | |
| Unknown | 18 | 31 |
Welch t-test, 2 sided
Fisher’s exact test, 2-sided
MOC = mucinous ovarian carcinoma. SD = standard deviation