Table 2.
Final best fit models for each cell type.
| Final models | Total WBC Estimate (SE) | Lymphocytes Estimate (SE) | Monocytes Estimate (SE) | Neutrophils Estimate (SE) | Log-eosinophils Estimate (SE) | Basophils Estimate (SE) |
|---|---|---|---|---|---|---|
|
| ||||||
| Fixed effects | ||||||
| Intercept | 5.41*** (0.28) | 1669*** (84) | 475*** (24) | 3103*** (251) | 4.97*** (0.14) | 28.6*** (2.8) |
| Session | 0.14 (.22) | −57 (101) | 23 (23) | 171 (221) | −0.21* (0.08) | − 0.1 (2.3) |
| Time (30 mins) | 0.51*** (0.09) | 8(33) | −8 (13) | 506*** (92) | −0.02 (0.06) | 2.7† (1.5) |
| Time (90 mins) | 0.87*** (0.09) | 85* (33) | 1 (13) | 785*** (93) | −0.03 (0.06) | 5.0** (1.5) |
| Time (240 mins) | 0.90*** (0.10) | 321*** (34) | 2 (13) | 566*** (94) | −0.05 (0.06) | 4.3** (1.5) |
| Interaction: session × time (30 mins) | − 0.01(0.19) | −102 (65) | −33 (26) | 128 (183) | − | 1.3(3.1) |
| Interaction: session × time (90 mins) | 0.17 (0.19) | −205** (67) | −43† (26) | 438* (185) | − | 1.5(3.1) |
| Interaction: session × time (240 mins) | 0.43† (0.19) | 35 (68) | −7 (27) | 446* (188) | − | 7.3* (3.1) |
| ELA-status | 0.95 (0.69) | 35 (165) | 27 (71) | 998 (619) | 0.39(.35) | 9.9(6.0) |
| Interaction: session × ELA | 0.42 (0.44) | - | 30 (45) | - | - | - |
| Interaction: ELA × time (30 mins) | 0.57** (0.19) | - | −14 (26) | 474* (184) | - | - |
| Interaction: ELA × Time (90 mins) | 0.44* (0.19) | - | 6(26) | 358† (185) | - | - |
| Interaction: ELA × Time (240 mins) | 0.35† (0.19) | - | −71** (26) | 312† (188) | - | - |
| Interaction: session × ELA × time (30 mins) | −0.12 (0.38) | - | −29 (52) | - | - | - |
| Interaction: session × ELA × time (90 mins) | 0.12 (0.38) | - | 1 (52) | - | - | - |
| Interaction: session × ELA × time (240 mins) | −0.36 (0.39) | - | 19 (53) | - | - | - |
| Age | −0.02 (0.19) | 57 (50) | 13 (20) | −139 (179) | 0.28* (0.10) | 2.8 (1.8) |
| Sex | −0.97 (0.51) | −106 (129) | −27 (53) | −980* (462) | 0.75** (0.26) | −10.6* (4.6) |
| Minority | 0.20 (0.49) | 10 (127) | −24 (51) | 337 (441) | 0.43(.25) | 1.1 (4.4) |
| SES | 0.02 (0.31) | 44 (81) | −23 (32) | 22 (283) | −0.41* (0.16) | −4.6 (2.8) |
| BMI | 0.09 (0.09) | −33 (23) | −3 (10) | 127 (84) | 0.02 (0.05) | −0.9 (0.84) |
| Random effects | ||||||
| Subject-level variance | 1.29 (0.35) | 122851 (35045) | 12873 (3553) | 1046217 (286159) | 0.34 (0.09) | 129 (37) |
| Session-intercept Covariance | 0.22 (0.23) | −111358 (42040) | 224 (2155) | 212794 (208364) | 0.04 (0.05) | 44 (19) |
| Session variance | 0.83 (0.26) | 229497 (69686) | 4964 (2162) | 884145 (272489) | 0.15 (0.05) | 20 (15) |
| Residual variance | 0.25 (0.03) | 30762 (3454) | 4678 (525) | 235672 (26115) | 0.08 (0.009) | 66 (7) |
See supplemental digital content Tables S5–S10 for model iterations for each cell type. Bold values indicate significance as follows:
†
p < .10
*
p < .05
**
p < .01
***
p < .001.