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. 2022 Nov 28;17(11):e0277920. doi: 10.1371/journal.pone.0277920

Table 2. Characteristics.

Non-responder Responder p value
(N = 12) (N = 36)
Age (years; mean ± SD) 69.1 ± 4.3 66.8 ± 10.3 0.485057
Gender (no.; Male: Female) 5: 7 25: 11 0.08519
HbA1c (%) 7.5 ± 1.5 8.2 ± 1.2 0.344098
Pre-treatment BCVA at visit 1 69.6 ± 14.3 66.7 ± 16.2 0.585873
(ETDRS letters; mean ± SD)
BCVA at visit 2 69.6 ± 14.2 69.2 ± 13.3 0.931332
(ETDRS letters; mean ± SD)
BCVA at visit 3 69.1 ± 14.5 68.8 ± 13.4 0.956494
(ETDRS letters; mean ± SD)
BCVA at visit 4 67.3 ± 16.3 71.8 ± 14.0 0.359004
(ETDRS letters; mean ± SD)
Improvement BCVA -2.3 ± 4.4 5.1 ± 7.7 0.003007
(ETDRS letters; mean ± SD)
Pre-treatment CRT at visit1 373 ± 139 389 ± 129 0.725201
(μm; mean ± SD)
CRT at visit 2 (μm; mean ± SD) 363 ± 145 295 ± 112 0.0968551
CRT at visit 3 (μm; mean ± SD) 387 ± 133 275 ± 129 0.0125176
CRT at visit 4 (μm; mean ± SD) 381 ± 140 253 ± 111 0.0023279
Improvement CRT rate -4.7 ± 23.3 32.9 ± 20.4 0.00000286569
(%; mean ± SD)
Pre-treatment IOP 14.7 ± 3.5 14.8 ± 3.2 0.879601
(mmHg; mean ± SD)