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. 2022 Nov 28;17(11):e0278245. doi: 10.1371/journal.pone.0278245

Table 1. Demographic features of the participants included to the mutation analysis.

MS patients Controls
Number 94** 99
RMS/SPMS/PPMS 80/10/4 -
Median age (range) 37 yrs (20–68) 35 yrs (19–70)
Mean age 39.4 yrs 39.8 yrs
Percentage females 72% 71%
EDSS* mean/median (range) 2.4/2.0 (0–6.5) -

RMS, relapsing MS; SPMS, secondary progressive MS; PPMS, primarily progressive MS;

*EDSS, Expanded disability scale score at the time of sampling.

**Four MS patients were excluded from the mutation analysis, because their samples had low sequencing coverages.