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. 2022 Nov 28;17(11):e0273256. doi: 10.1371/journal.pone.0273256

Table 1. Predicted antiviral activities (% inhibition) of cytidine derivatives 2–15, remdesivir, and AZT.

Compounds General HBV HCV HHV HIV
1 - - - - -
2 56.694 24.616 52.294 39.139 60.776
3 50.334 25.168 44.745 68.231 69.760
4 51.770 25.164 44.746 65.844 70.174
5 7.689 20.217 18.367 48.010 71.148
6 5.209 22.034 17.707 32.962 62.485
7 8.964 19.478 38.064 46.137 65.673
8 54.817 25.306 58.732 51.525 55.146
9 2.101 19.505 44.539 44.016 68.671
10 2.327 19.694 37.089 45.767 68.719
11 50.134 24.790 47.106 60.254 62.961
12 4.310 20.681 37.091 43.999 69.047
13 3.345 19.376 56.274 81.466 65.758
14 47.021 26.981 46.291 75.321 63.214
15 61.039 18.367 53.816 61.409 63.427
Remdesivir 48.642 22.443 66.968 36.291 69.503
AZT 87.038 19.619 24.962 28.728 92.855

HBV = Hepatitis B virus; HCV = Hepatitis C virus; HHV = Human herpesvirus; HIV = Human immunodeficiency virus.