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. 2022 Nov 28;17(11):e0278213. doi: 10.1371/journal.pone.0278213

Table 1. Clinical characteristics, laboratory tests, signs and symptoms, and comorbidities.

Total (N = 280) Survivors (N = 192) Non-survivors (N = 88) p-value
Clinical characteristics
Sex (M/F) % 54/46 55/45 53/47 -
Age (years) 62.42 (1.45) 58.54 (1.22) 70.87 (1.64) <0.001*
RR (rpm) 23.07 (0.52) 22.51 (0.70) 24.29 (0.93) 0.150
HR (bpm) 86.48 (1.08) 87.82 (1.25) 83.56 (2.21) 0.094
SBP (mmHg) 132.7 (1.61) 134.78 (1.97) 128.18 (3.03) 0.068
SpO2 (%) 93 (0.37) 95 (0.27) 91 (0.94) <0.001*
Laboratory tests
Hemoglobin (g/dL) 12.68 (0.12) 12.83 (0.14) 12.36 (0.23) 0.077
Leukocytes (mm3) 11.47 (0.36) 10.30 (0.40) 14.03 (0.69) <0.001*
Platelets (mm3) 269.4 (6.86) 276 (8.57) 255 (11.87) 0.168
Creatinine (mg/dL) 1.46 (0.14) 1.32 (0.17) 1.76 (0.21) 0.127
Urea (mg/dL) 58.32 (46.47) 44.52 (2.43) 85.28 (6.51) <0.001*
Signs and Symptoms
Days to hospitalization (days) 8.40 (0.30) 8.79 (0.37) 7.55 (0.50) 0.057*
Dyspnea (%) 82 77 92 0.003
Cough (%) 59 60 58 0.925
Fever (%) 57 58 56 0.838
Muscular pain (%) 22 25 16 0.102
Headache (%) 15 15 14 0.800
Ageusia (%) 6 7 6 0.934
Anosmia (%) 11 15 5 0.019*
Runny nose (%) 2 3 2 0.991
Sore throat (%) 2 3 3 0.991
Asthenia (%) 10 12 6 0.126
Joint pain (%) 1 1 1 0.579
Nausea and/or vomit (%) 6 8 5 0.543
Fatigue (%) 2 4 1 0.433
Comorbidities††
Number of comorbidities 1.40 (0.67) 1.28 (0.07) 1.66 (0.12) 0.007*
SAH (%) 53 55 53 0.787
Diabetes (%) 67 30 39 0.178
Obesity (%) 24 23 27 0.522
COPD (%) 3 3 5 0.489
Others cardiopaties (%) 10 6 17 0.005
CKD (%) 4 4 5 0.977
Athsma (%) 2 3 2 0.804
Clinical Evolution
Hospital LOS (days) 6.02 (0.40) 5 (0.95) 8.81 (0.92) <0.001*
IMV duration (days) 1.74 (0.38) 0.53 (0.33) 4.38 (0.65) <0.001*

M: Male, F: Female, RR: Respiratory rate, HR: Heart rate, SBP: Systolic blood pressure, SpO2: Peripheral oxygen saturation, SAH: Systemic arterial hypertension, CKD: Chronic kidney disease, IMV: Invasive mechanical ventilation, LOS: Length of stay, COPD: Chronic obstructive pulmonary disease, rpm: Respiration per minute, bpm: Beats per minute, mmHg: Millimeters of mercury, %: Percentage, g: Grams, mg: Milligrams, dL: Deciliters, mm: Millimeters. Data presented as mean and standard error.

*Comparison between groups using Chi2 test (categorical variables) or unpaired t-test (numerical variables).

Proportions represent the number of people who presented that signs or symptoms.

††Proportions represent the number of people who had that comorbidity.