FIG. 6.

Effect of anti-CdtC MAbs on the ability of H. ducreyi to inhibit proliferation of Jurkat cells. Varying amounts of hybridoma culture supernatants containing the CdtC-neutralizing MAb 9E9 (open squares) or its isotype control (filled squares) were incubated with or without FTWC (3 μg/ml). Jurkat T cells were added to wells and incubated for 24 h. Results are expressed as the percentages of inhibition of [³H]thymidine incorporation in wells without FTWC and the means ± standard errors of triplicate wells and are representative of three independent experiments.