Table 2.
Correlation coefficients between four different centralities for 336 residues of PKA calculated in PRNs based on an SS, NW PRN (NW), and PRNs weighted using CC, LMI, and LSP alignment (LSP)
| SS | NW | CC | LMI | |
|---|---|---|---|---|
| DC | ||||
| NW | 0.91 | |||
| CC | 0.72 | 0.85 | ||
| LMI | 0.80 | 0.93 | 0.97 | |
| LSP | 0.67 | 0.75 | 0.66 | 0.65 |
| BC | ||||
| NW | 0.84 | |||
| CC | 0.58 | 0.71 | ||
| LMI | 0.43 | 0.50 | 0.68 | |
| LSP | 0.38 | 0.47 | 0.48 | 0.18 |
| CL | ||||
| NW | 0.97 | |||
| CC | 0.88 | 0.91 | ||
| LMI | 0.82 | 0.84 | 0.94 | |
| LSP | 0.84 | 0.89 | 0.87 | 0.73 |
| EG | ||||
| NW | 0.75 | |||
| CC | −0.25 | 0.27 | ||
| LMI | −0.25 | 0.29 | 0.98 | |
| LSP | 0.78 | 0.55 | −0.21 | −0.21 |
Sixteen-ns trajectories were used for the MD simulation–based PRNs.