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. Author manuscript; available in PMC: 2022 Nov 28.
Published in final edited form as: J Am Coll Cardiol. 2018 Nov 13;72(20):2431–2439. doi: 10.1016/j.jacc.2018.08.2173

Table 2.

Association of Race with Sudden Cardiac Death among Participants without Baseline Cardiovascular Disease

Participants (n=22,507) White
(n=13,091)
Black
(9,416)
p-value
Sudden Cardiac Death Events, n 67 107
Incidence Rate* (per 1,000 py) 0.7 (0.6, 0.9) 1.8 (1.4, 2.2)
Unadjusted; HR (95% CI) 1.00 2.35 (1.74, 3.20) <0.001
Model 1 1.00 2.35 (1.70, 3.24) <0.001
Model 2 1.00 1.89 (1.35, 2.66) <0.001
Model 3§ 1.00 1.98 (1.41, 2.80) <0.001
Model 4 1.00 1.88 (1.33, 2.67) <0.001
Model 5# 1.00 1.97 (1.39, 2.77) <0.001
*

Age-adjusted

Model 1 adjusts for age, sex, region, education, income, and health insurance

Model 2 adjusts for Model 1 plus standard coronary heart disease risk factors and preventive therapies including systolic blood pressure, diastolic blood pressure, total cholesterol, HDL, diabetes, body mass index, statins, and use of antihypertensive medication

§

Model 3 adjusts for Model 2 plus ACR, eGFR, LVH, and atrial fibrillation

Model 4 adjusts for Model 3 plus behavioral factors including smoking, alcohol use, physical activity, perceived stress and elevated depressive symptoms

#

Model 5 adjusts for Model 4 plus intervening non-fatal myocardial infarction and/or heart failure hospitalization as time-variant covariates and the competing risks of non-SCD