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. 2022 Jul 21;43(18):5432–5451. doi: 10.1002/hbm.26019

TABLE 2.

Tabulated results of the metabolite and hormone analysis

Lean (n = 10) Overweight (n = 13) p values
IN‐PLA IN‐INS IN‐PLA IN‐INS Treatment Group Treatment × group interaction
plasma glucose (mmol/l) −0.05 (0.28) −0.2 (0.2) 0 (0.1) −0.1 (0.4) .031* .63 .48
serum insulin (mIU/l) −0.15 (1.18) −0.75 (13.68) −1.4 (2,9) 2.0 (8.8) .41 .33 .61
serum C‐peptide (pmol/l) −46.5 (64.75) a −103.5 (96.75) a −69.0 (68) −111 (198) .015* .70 .880

Note: Analysis was conducted on (post–pre) levels. A significant treatment effect was seen for serum C‐peptide. Lean (n = 10), OW (n = 13). * p < .05. Data are presented as median (IQR).

a

Significant post hoc test, that describes IN‐INS associated C‐peptide suppression over time as greater than IN‐PLA for the lean group only.