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. 2022 Jul 1;206(9):1081–1095. doi: 10.1164/rccm.202202-0309OC

Figure 6.


Figure 6.

High-resolution deconvolution immunofluorescence microscopy of mucin granules in human airways. (A) Deconvolved image of secretory cells in a human proximal airway stained with antibodies against MUC5AC (red) and MUC5B (green). Scale bar, 5 μm. (B) Higher magnification of the boxed region in A showing mucin granules containing both mucins and a central lucency (white arrowheads). Scale bar, 1 μm. (C) Deconvolved image of secretory cells in a human distal airway stained with the same antibodies. Scale bar, 5 μm. (D) Higher magnification of the boxed region in C. Scale bar, 1 μm. MUC5AC = mucin 5AC, oligomeric gel-forming; MUC5B = mucin 5B, oligomeric gel-forming.