Table 2.

Univariate Cox proportional hazards analysis of all-cause mortality by prognostic factors in adult patients with glioblastoma.

Characteristic	HR (95%CI)	P
Gender
Male	Reference	.647
Female	0.976 (0.881–1.082)
Age
18–40	Reference	.000
40–60	2.185 (1.528–3.124)	.021
60–80	4.333 (3.052–6.153)	.010
80-	7.714 (5.326–11.172)	.000
Race
White	Reference	.113
Black	1.010 (0.808–1.262)
Asian or pacific islander	0.737 (0.552–0.982)
Grade
Grade 1–2	Reference	.000
Grade 3–4	15.151 (8.928–25.713)
Laterality
Left - origin of primary	Reference	.001
Right - origin of primary	1.018 (0.887–1.169)	.080
Bilateral	1.533 (0.943–2.491)	.059
Not a paired site	1.227 (1.086–1.387)	.125
Surgery
No	Reference	.000
Yes	0.494 (0.437–0.559)
Radiation
No	Reference	.000
Yes	0.472 (0.422–0.528)
Chemotherapy recode
No	Reference	.000
Yes	0.501 (0.453–0.555)
Year at diagnosis
1975–1985	Reference	.499
1985–1995	0.824 (0.552–1.230)	.073
1995–2005	0.948 (0.652–1.379)	.354
2005–2016	0.931 (0.643–1.348)	.200

HR = hazard ratio.