Table 1.
Inconsistency factors of all comparisons.
| Outcome | Cycle | IF and 95% CI | P value |
|---|---|---|---|
| 4 wk healing rates | Ome-Pan-Pla | IF = 0.637, 95% CI (0.00, 1.51) | .153 |
| Ome-Lan-Pan | IF = 0.404, 95% CI (0.00, 1.01) | .190 | |
| Lan-Pan-Pla | IF = 0.383, 95% CI (0.00, 1.29) | .410 | |
| Lan-Pan-Eso | IF = 0.302, 95% CI (0.00, 0.82) | .250 | |
| Ome-Pan-Eso | IF = 0.213, 95% CI (0.00, 0.77) | .455 | |
| Ome-Lan-Pla | IF = 0.194, 95% CI (0.00, 0.78) | .518 | |
| Ome-Lan-Eso | IF = 0.086, 95% CI (0.00, 0.58) | .736 | |
| 8 wk healing rates | Ome-Pan-Rab | IF = 1.017, 95% CI (0.00, 2.85) | .277 |
| Ome-Pan-Eso | IF = 0.541, 95% CI (0.00, 1.23) | .124 | |
| Ome-Lan-Eso | IF = 0.417, 95% CI (0.00, 0.88) | .077 | |
| Ome-Lan-Pan | IF = 0.404, 95% CI (0.00, 1.07) | .237 | |
| Lan-Pan-Eso | IF = 0.303, 95% CI (0.00, 0.95) | .356 | |
| Ome-Pan-Pla | IF = 0.117, 95% CI (0.00, 0.96) | .785 | |
| Lan-Pan-Pla | IF = 0.104, 95% CI (0.00, 1.00) | .820 | |
| Ome-Lan-Pla | IF = 0.224, 95% CI (0.00, 0.80) | .448 | |
| Adverse event rates | Ome-Pan-Von | IF = 0.414, 95% CI (0.00, 1.46) | .437 |
| Ome-Pan-Eso | IF = 0.387, 95% CI (0.00, 1.12) | .302 | |
| Ome-Lan-Eso | IF = 0.173, 95% CI (0.00, 0.83) | .608 |
CI = confidence interval; Eso = esomeprazole, 40 mg/d; IF = inconsistency factor; Ila = ilaprazole, 10 mg/d; Lan = lansoprazole, 30 mg/d; Ome = omeprazole, 20 mg/d; Pan = pantoprazole, 40 mg/d; PLA = placebo; Rab = rabeprazole, 20 mg/d; Von = vonoprazan 20 mg/d.