Table 2.
Results of network meta-analyses for the rate of healing at 4 and 8 wk.
| OR (95% CI) | |||||||
|---|---|---|---|---|---|---|---|
| Ome | 1.17 (0.94, 1.45) | 1.31 (1.01, 1.69)* | 0.84 (0.54, 1.32) | 1.56 (1.29, 1.89)* | 1.73 (1.11, 2.71)* | 1.52 (0.91, 2.55) | 0.09 (0.06, 0.13)* |
| 0.94 (0.78, 1.14) | Lan | 1.12 (0.84, 1.48) | 0.72 (0.44, 1.19) | 1.34 (1.08, 1.66)* | 1.48 (0.94, 2.34) | 1.30 (0.81, 2.09) | 0.08 (0.05, 0.11)* |
| 0.87 (0.71, 1.08) | 0.93 (0.74, 1.17) | Pan | 0.64 (0.39, 1.07) | 1.20 (0.94, 1.51) | 1.33 (0.83, 2.12) | 1.16 (0.67, 2.01) | 0.07 (0.05, 0.10)* |
| 1.13 (0.78, 1.64) | 1.19 (0.79, 1.81) | 1.29 (0.84, 1.97) | Rab | 1.86 (1.14, 3.02)* | 2.06 (1.10, 3.87)* | 1.81 (0.91, 3.58) | 0.11 (0.06, 0.19)* |
| 0.68 (0.59, 0.79)* | 0.72 (0.61, 0.86)* | 0.78 (0.65, 0.94)* | 0.61 (0.41, 0.91)* | Eso | 1.11 (0.74, 1.66) | 0.97 (0.58, 1.63) | 0.06 (0.04, 0.08)* |
| 0.63 (0.42, 0.94)* | 0.67 (0.44, 1.01) | 0.72 (0.48, 1.09) | 0.56 (0.32, 0.97)* | 0.92 (0.64, 1.34) | Ila | 0.88 (0.46, 1.69) | 0.05 (0.03, 0.09)* |
| 0.74 (0.48, 1.14) | 0.78 (0.53, 1.16) | 0.84 (0.53, 1.33) | 0.65 (0.37, 1.16) | 1.08 (0.70, 1.66) | 1.17 (0.66, 2.06) | Von | 0.06 (0.03, 0.11)* |
| 9.33 (6.65, 13.11)* | 9.90 (7.07, 13.86)* | 10.67 (7.42, 15.33)* | 8.29 (5.01, 13.72)* | 13.66 (9.68, 19.29)* | 14.78 (8.89, 24.56)* | 12.67 (7.55, 21.29)* | Pla |
Results of 4 wk healing rates were listed in right upper triangles and results of 8 wk healing rates were listed in left lower triangles.
CI = confidence interval; Eso = esomeprazole, 40 mg/d; Ila = ilaprazole, 10 mg/d; Lan = lansoprazole, 30 mg/d; Ome = omeprazole, 20 mg/d; OR = odds ratio; Pan = pantoprazole, 40 mg/d; PLA = placebo; Rab = rabeprazole, 20 mg/d; Von = vonoprazan 20 mg/d.
*
Significant difference between two treatments.