Table 2.
Effect of bromelain (Bro), aluminum chloride (AlCl3), and their combination (Bro+AlCl3) on the hematological parameters in rats.
| Parameters | Groups | |||
|---|---|---|---|---|
| Cont. | Bro | AlCl3 | Bro+AlCl3 | |
| RBCs (x 106/μL) | 8.03a ± 0.274 | 8.41a ± 0.246 | 5.78b ± 0.264 | 8.33a ± 0.345 |
| WBCs (x 106/μL) | 10.97b ± 0.193 | 11.51b ± 0.418 | 13.23a ± 0.387 | 11.96b ± 0.340 |
| Hemoglobin (g/dl) | 13.20a ± 0.205 | 13.82a ± 0.455 | 9.51c ± 0.197 | 11.79b ± 0.202 |
| Platelets (103/μL) | 427c ± 12.08 | 427c ± 14.86 | 527a ± 13.59 | 470b ± 13.63 |
| PCV (%) | 47.16a ± 1.65 | 47.16a ± 1.42 | 38.10c ± 1.07 | 42.09b ± 1.25 |
| MCV (fl) | 63.58a ± 1.90 | 66.28a ± 1.99 | 65.80a ± 1.99 | 65.47a ± 2.11 |
| MCH (pg) | 18.90a ± 0.620 | 19.18a ± 0.487 | 19.90a ± 0.528 | 19.47a ± 0.603 |
| MCHC (%) | 32.59a ± 0.298 | 32.46a ± 0.301 | 31.93a ± 0.506 | 31.99a ± 0.415 |
| Neutrophils (%) | 19.14b ± 0.459 | 19.7b ± 0.522 | 23.29a ± 0.837 | 20.71b ± 0.680 |
| Lymphocytes (%) | 58.13a ± 0.527 | 56.26ab ± 2.15 | 45.36c ± 1.20 | 52.75b ± 1.28 |
| Eosinophils (%) | 1.57a ± 0.297 | 1.60a ± 0.170 | 1.54a ± 0.177 | 1.58a ± 0.276 |
| Monocytes (%) | 4.19a ± 0.142 | 4.07a ± 0.170 | 4.36a ± 0.180 | 4.17a ± 0.166 |
RBC: red blood cell; WBC: white blood cell; hb: hemoglobin; PCV: packed cell volume; MCV: mean cell volume; MCH: mean corpuscular hemoglobin; MCHC: mean corpuscular hemoglobin concentration. Values are expressed as means ± SEM; n = 7 for each treatment group. abc Mean values within a row not sharing a common superscript letter were significantly different, P < 0.05. Statistically significant variations are compared as follows: Bromelain and AlCl3 groups are compared vs the control group while Bromelain+AlCl3 group is compared vs the AlCl3 group.