Table 3.
Effect of bromelain (Bro), aluminum chloride (AlCl3) and their combination (Bro+AlCl3) on the level of thiobarbituric acid reactive substances (TBARS), hydrogen peroxide (H2O2), and reduced glutathione (GSH) content in rat liver.
| Parameters | Groups | |||
|---|---|---|---|---|
| Cont. | Bro | AlCl3 | Bro+AlCl3 | |
| TBARS (nmol/g tissue) % change |
30.20c ± 0.899 | 23.49d ± 0.599 (-22.22%) |
44.49a ± 1.28 (+47.33%) |
36.31b ± 0.928 (+20.25%) |
| H2O2 (μmol/g tissue) % change |
63.65c ± 1.62 | 50.35d ± 1.36 (-20.90) |
90.26a ± 1.45 (+41.81%) |
78.92b ± 2.02 (+23.98%) |
| GSH (mmol/mg protein) % change |
1.72b ± 0.052 | 2.05a ± 0.061 (+19.37%) |
0.99d ± 0.031 (-42.27%) |
1.39c ± 0.041 (-18.95%) |
Values are expressed as means ± SEM; n = 7 for each treatment group. abcd Mean values within a row not sharing a common superscript letter were significantly different, P < 0.05. Statistically significant variations are compared as follows: Bromelain and AlCl3 groups are compared vs control group while Bromelain+AlCl3 group is compared vs AlCl3 group.