Table 4.
Effect of bromelain (Bro), aluminum chloride (AlCl3), and their combination (Bro+AlCl3) on the activities of antioxidant enzymes in rat liver.
| Parameters | Groups | |||
|---|---|---|---|---|
| Cont. | Bro | AlCl3 | Bro+AlCl3 | |
| SOD (U/mg protein) % change |
75.93b ± 2.25 | 91.38a ± 3.19 (+20.35%) |
38.83d ± 1.16 (-48.86%) |
60.46c ± 1.64 (-20.37%) |
| CAT (μmol/hr/mg protein) % change |
46.07b ± 1.62 | 54.85a ± 1.82 (+19.05%) |
25.39d ± 0.574 (-44.89%) |
35.72c ± 1.08 (-22.47%) |
| GPx (U/mg protein) % change |
1.07b ± 0.038 | 1.26a ± 0.041 (+18.08%) |
0.60d ± 0.021 (-43.66%) |
0.85c ± 0.025 (-20.66%) |
| GR (U/mg protein) % change |
1.23b ± 0.042 | 1.46a ± 0.036 (+18.77%) |
0.70d ± 0.023 (-42.53%) |
0.99c ± 0.033 (-19.46%) |
| GST (μmol/hr/mg protein) % change |
1.26b ± 0.032 | 1.50a ± 0.045 (+19.23%) |
0.67d ± 0.022 (-46.93%) |
0.99c ± 0.027 (-21.22%) |
Values are expressed as means ± SEM; n = 7 for each treatment group. abcd Mean values within a row not sharing a common superscript letter were significantly different, P < 0.05. Statistically significant variations are compared as follows: Bromelain and AlCl3 groups are compared vs control group while Bromelain+AlCl3 group is compared vs AlCl3 group.