Table 3. Factors associated with low 5-level version of the EuroQol 5-dimensional questionnaire index values at follow-up.

Characteristics	OR (95% CI)	P value
Age ≥ 55	1.37 (0.59–3.16)	0.157
Female sex	3.27 (1.18–9.08)	0.020*
≥ 3 symptoms at baseline	3.96 (1.39–11.27)	0.010*
Metabolic disease	2.57 (1.01–6.50)	0.047*
Constitutional symptoms at baseline	3.57 (1.55–8.21)	0.003*
Cardiopulmonary symptoms at baseline	2.56 (0.67–9.81)	0.170
Neurological symptoms at baseline	5.21 (2.17–12.51)	< 0.001***
Neuropsychiatric symptoms at baseline	11.14 (4.03–30.76)	< 0.001***
Constitutional symptoms at follow-up	7.30 (2.86–18.66)	< 0.001***
Cardiopulmonary symptoms at follow-up	18.60 (6.11–56.63)	< 0.001***
Neurological symptoms at follow-up	7.54 (3.20–17.76)	< 0.001***
Neuropsychiatric symptoms at follow-up	19.27 (5.27–70.47)	< 0.001***

OR = odds ratio, CI = confidence interval.

^*P < 0.05; ^***P < 0.001.