Table 4. Factors associated with organ-system symptoms and low 5-level version of the EuroQol 5-dimensional questionnaire index values at follow-up.

Symptoms at follow-up	Factors	OR (95% CI)	P value
Constitutional	Age ≥ 55	2.17 (0.81–5.83)	0.125
	Female sex	8.84 (2.19–35.59)	0.002**
	Metabolic disease	2.72 (0.92–8.05)	0.070
	Constitutional symptom at baseline	3.90 (1.31–11.60)	0.015*
Neurological	Age ≥ 55	0.69 (0.26–1.82)	0.453
	Female sex	2.79 (0.77–10.04)	0.117
	Metabolic disease	2.77 (0.90–8.56)	0.077
	Neurological symptom at baseline	2.71 (1.05–7.01)	0.040*
Neuropsychiatric	Age ≥ 55	1.27 (0.38–4.23)	0.693
	Female sex	3.10 (0.56–17.24)	0.197
	Metabolic disease	3.43 (0.82–14.42)	0.092
	Neuropsychiatric symptom at baseline	9.60 (2.41–38.21)	0.001**

OR = odds ratio, CI = confidence interval.

^*P < 0.05; ^**P < 0.01.