Table 5. Subgroup analysis for the factors associated with symptoms and low 5-level version of the EuroQol 5-dimensional questionnaire index values at follow-up.

Symptoms at follow-up		Factors	OR (95% CI)	P value
Constitutional
	Fatigue	Female sex	9.09 (2.03–40.70)	0.004**
		Metabolic disease	5.11 (1.47–17.75)	0.010*
		Fatigue at baseline	3.50 (1.0006–12.25)	0.050*
	Myalgia	Female sex	2.85 (0.64–12.78)	0.171
		Metabolic disease	2.48 (0.55–11.21)	0.239
		Myalgia at baseline	N/A	N/A
Neurological
	Memory impairment	Female sex	3.17 (0.54–18.65)	0.202
		Metabolic disease	1.82 (0.42–7.87)	0.424
		Memory impairment at baseline	N/A	N/A
	Hyposmia	Female sex	1.62 (0.25–10.25)	0.611
		Metabolic disease	9.88 (1.001–97.42)	0.050*
		Hyposmia at baseline	0.48 (0.08–2.82)	0.420
	Hypogeusia	Female sex	1.10 (0.08–15.22)	0.942
		Metabolic disease	5.46 (0.34–88.08)	0.232
		Hypogeusia at baseline	4.03 (0.31–53.25)	0.289
	Dizziness	Female sex	2.48 (0.31–20.02)	0.393
		Metabolic disease	17.83 (1.56–203.79)	0.020*
		Dizziness at baseline	1.48 (0.14–15.39)	0.742
Neuropsychiatric
	Anxiety	Female sex	3.33 (0.24–45.94)	0.370
		Metabolic disease	7.79 (0.88–68.82)	0.068
		Anxiety at baseline	16.06 (2.69–96.06)	0.002**

OR = odds ratio, CI = confidence interval, N/A = not available.

^*P < 0.05; ^**P < 0.01.