Table 5. Registry of Severe Cutaneous Adverse Reactions (RegiSCAR) scoring system.
Total score: <2: Excluded ; 2-3: Possible ; 4-5:Probable; ≥6: Definite
BSA: body surface area; HAV: hepatitis A virus; HBV: hepatitis B virus; HCV: hepatitis C virus; ANA: antinuclear antibodies
Item | -1 | 0 | +1 | Additional points | Our patient |
Fever >101.3F | No | Yes | -1 | ||
Enlarged lymph node >1cm | No | Yes | 0 | ||
Eosinophilia ≥0.7 × 109 | No | Yes | 2 points if >1.5 x 109 | 2 | |
Atypical lymphocytes | No | Yes | 1 | ||
Rash suggestive of DRESS: => facial edema, purpura, infiltration, desquamation. | No | Unknown | Yes | 1 | |
Extent ≥50% of BSA | No/Unkown | Yes | 1 | ||
Skin biopsy suggestive of DRESS | No | Yes/Unknown | 0 | ||
Organ involvement: 1 point for each organ involvement. | No | Yes | maximum score: 2 | 1 | |
Disease duration ≥15 days | No/Unknown | Yes | 0 | ||
Exclusion of other causes; add 1 point if 3 of the following tests are excluded: HAV, HBV, HCV, mycoplasma, chlamydia, ANA, blood culture. | No/Unknown | Yes | 1 | ||
Final score | 6 |