Table 1.
Grade group 1 | Grade group 2 | p* | |||||
---|---|---|---|---|---|---|---|
PSA < 10 ng/mL (N = 15,301) | PSA 10–20 ng/mL (N = 1731) | p | PSA < 10 ng/mL (N = 8367) | PSA 10–20 ng/mL (N = 1149) | p | ||
Age at diagnosis, year | 59.7 ± 7.0 | 61.8 ± 6.8 | <0.001 | 61.5 ± 6.9 | 62.9 ± 6.8 | <0.001 | <0.001 |
Race/ethnicity | <0.001 | 0.004 | 0.067 | ||||
White | 12,649 (82.7%) | 1330 (76.8%) | 6813 (81.4%) | 889 (77.4%) | |||
Black | 1769 (11.5%) | 259 (15.0%) | 1038 (12.4%) | 176 (15.3%) | |||
Others/unknown | 883 (5.8%) | 142 (8.2%) | 516 (6.2%) | 84 (7.3%) | |||
Clinical T stage | 0.247 | 0.001 | <0.001 | ||||
T1 | 11,271 (73.7%) | 1298 (75.0%) | 5872 (70.2%) | 860 (74.8%) | |||
T2 | 4030 (26.3%) | 433 (25.0%) | 2495 (29.8%) | 289 (25.2%) | |||
PSA, ng/mL | 5.1 ± 1.9 | 13.1 ± 2.7 | <0.001 | 5.4 ± 1.9 | 12.9 ± 2.6 | <0.001 | <0.001 |
% Positive cores | 17.1 ± 8.0 | 16.6 ± 8.1 | 0.026 | 19.2 ± 7.7 | 18.9 ± 7.9 | 0.226 | <0.001 |
Insurance | <0.001 | <0.001 | 0.702 | ||||
Insured | 14,723 (96.2%) | 1619 (93.5%) | 8072 (96.5%) | 1060 (92.3%) | |||
Medicaid | 422 (2.8%) | 85 (4.9%) | 204 (2.4%) | 69 (6.0%) | |||
Uninsured | 156 (1.0%) | 27 (1.6%) | 91 (1.1%) | 20 (1.7%) | |||
Marital status | <0.001 | <0.001 | <0.001 | ||||
Married | 12,729 (83.2%) | 1341 (77.5%) | 6783 (81.1%) | 874 (76.1%) | |||
Single | 2572 (16.8%) | 390 (22.5%) | 1584 (18.9%) | 275 (23.9%) | |||
Pathologic upgrading at RP | <0.001 | <0.001 | <0.001 | ||||
No | 14,410 (94.2%) | 1530 (88.4%) | 7002 (83.7%) | 875 (76.2%) | |||
Yes | 891 (5.8%) | 201 (11.6%) | 1365 (16.3%) | 274 (23.8%) | |||
Pathologic upstaging at RP | <0.001 | <0.001 | <0.001 | ||||
No | 14,149 (92.5%) | 1478 (85.4%) | 6969 (83.3%) | 828 (72.1%) | |||
Yes | 1152 (7.5%) | 253 (14.6%) | 1398 (16.7%) | 321 (27.9%) | |||
Adverse pathology | <0.001 | <0.001 | <0.001 | ||||
No | 13,470 (88.0%) | 1349 (77.9%) | 6027 (72.0%) | 672 (58.5%) | |||
Yes | 1831 (12.0%) | 382 (22.1%) | 2340 (28.0%) | 477 (41.5%) |
PSA prostate-specific antigen, RP radical prostatectomy.
*p value between grade groups.