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. 2021 Sep 10;25(4):690–693. doi: 10.1038/s41391-021-00448-8

Table 1.

Baseline characteristics and pathological results according to biopsy grade group and PSA level.

Grade group 1 Grade group 2 p*
PSA < 10 ng/mL (N = 15,301) PSA 10–20 ng/mL (N = 1731) p PSA < 10 ng/mL (N = 8367) PSA 10–20 ng/mL (N = 1149) p
Age at diagnosis, year 59.7 ± 7.0 61.8 ± 6.8 <0.001 61.5 ± 6.9 62.9 ± 6.8 <0.001 <0.001
Race/ethnicity <0.001 0.004 0.067
White 12,649 (82.7%) 1330 (76.8%) 6813 (81.4%) 889 (77.4%)
Black 1769 (11.5%) 259 (15.0%) 1038 (12.4%) 176 (15.3%)
Others/unknown 883 (5.8%) 142 (8.2%) 516 (6.2%) 84 (7.3%)
Clinical T stage 0.247 0.001 <0.001
T1 11,271 (73.7%) 1298 (75.0%) 5872 (70.2%) 860 (74.8%)
T2 4030 (26.3%) 433 (25.0%) 2495 (29.8%) 289 (25.2%)
PSA, ng/mL 5.1 ± 1.9 13.1 ± 2.7 <0.001 5.4 ± 1.9 12.9 ± 2.6 <0.001 <0.001
% Positive cores 17.1 ± 8.0 16.6 ± 8.1 0.026 19.2 ± 7.7 18.9 ± 7.9 0.226 <0.001
Insurance <0.001 <0.001 0.702
Insured 14,723 (96.2%) 1619 (93.5%) 8072 (96.5%) 1060 (92.3%)
Medicaid 422 (2.8%) 85 (4.9%) 204 (2.4%) 69 (6.0%)
Uninsured 156 (1.0%) 27 (1.6%) 91 (1.1%) 20 (1.7%)
Marital status <0.001 <0.001 <0.001
Married 12,729 (83.2%) 1341 (77.5%) 6783 (81.1%) 874 (76.1%)
Single 2572 (16.8%) 390 (22.5%) 1584 (18.9%) 275 (23.9%)
Pathologic upgrading at RP <0.001 <0.001 <0.001
No 14,410 (94.2%) 1530 (88.4%) 7002 (83.7%) 875 (76.2%)
Yes 891 (5.8%) 201 (11.6%) 1365 (16.3%) 274 (23.8%)
Pathologic upstaging at RP <0.001 <0.001 <0.001
No 14,149 (92.5%) 1478 (85.4%) 6969 (83.3%) 828 (72.1%)
Yes 1152 (7.5%) 253 (14.6%) 1398 (16.7%) 321 (27.9%)
Adverse pathology <0.001 <0.001 <0.001
No 13,470 (88.0%) 1349 (77.9%) 6027 (72.0%) 672 (58.5%)
Yes 1831 (12.0%) 382 (22.1%) 2340 (28.0%) 477 (41.5%)

PSA prostate-specific antigen, RP radical prostatectomy.

*p value between grade groups.