Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2022 Apr 15;15(6):1257–1269. doi: 10.1038/s41385-022-00513-y

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Fig. 4 — B6.4get mice were infected with 200 L3 H. polygyrus and 7 days post-infection the small intestine and MLN collected for analysis. a Percentage (top) and total number (bottom) of IL-4(GFP)⁺ Th cells (TCRβ ⁺ CD4⁺ CD44⁺) in the SILP. b Percentage (top) and total number (bottom) of CXCR3⁺ Th cells in the SILP. c Representative flow cytometry scatter plot of IL-4⁺ (top) and CXCR3⁺ (bottom) Th cells from the SILP of D7 infected mice. d Percentage of CD44^hi of IL-4(GFP)⁺ (left) and CXCR3⁺ (right) from the SILP and MLN. e Representative overlaid histograms of IL-10R expression of IL-4⁺ and CXCR3⁺ Th cells compared to the IL-10R FMO control, in the SILP and MLN of day 7 infected mice. f Geometric mean of IL-10R expression and (g) percentage of IL-10⁺ cells of IL-4(GFP)⁺, CXCR3⁺ and DN (double negative) Th cells in the MLN and SILP. Graphed data are shown with means ± 1 SD and are pooled from three independent experiments with n = 3 per experiment. Statistical significance was calculated by Student’s t test and Kruskal–Wallis test with Dunn’s post-test for multiple comparisons between groups. (Significance *p < 0.05, ***p < 0.001, ****p < 0.0001).