Table 2.
Baseline OCT data.
| Region | Mean RNFL thickness (µm ± SE) | The difference from mean HV baseline RNFL thickness in µm (95% CI) | ||
|---|---|---|---|---|
| Healthy volunteers | Participants with MS | |||
| OS | OD | OS | OD | |
| Global | 98 ± 1.2 | 99 ± 1.3 | − 10 (− 14, − 5)*** | − 11 (− 15, − 7)*** |
| Temporal | 70 ± 1.3 | 71 ± 1.5 | − 11 (− 16, − 7)*** | − 12 (− 17, − 7)*** |
| Temporal inferior | 145 ± 2.3 | 142 ± 2.4 | − 15 (− 23, − 7)*** | − 13 (− 22, − 5)** |
| Temporal superior | 136 ± 1.9 | 136 ± 2.3 | − 10 (− 17, − 3)** | − 9 (− 15, − 2)* |
| Nasal | 74 ± 1.7 | 78 ± 2 | − 8 (− 13, − 3)** | − 11 (− 16, − 6)*** |
| Nasal inferior | 110 ± 2.9 | 113 ± 3 | − 5 (− 14, 4) | − 8 (− 17, 0) |
| Nasal superior | 108 ± 2.3 | 99 ± 2.2 | − 9 (− 17, − 1)* | − 9 (− 16, − 3)* |
| Mean macular volume (mm3 ± SE) | The difference from mean HV baseline macular volume in mm3 (95% CI) | |||
|---|---|---|---|---|
| Healthy volunteers | Participants with MS | |||
| OS | OD | OS | OD | |
| 8.68 ± 0.04 | 8.66 ± 0.04 | − 0.22 (− 0.35, − 0.08)** | − 0.3 (− 0.44, − 0.17)*** | |
The differences in mean baseline RNFL thickness and macular volume for MS participants when compared to healthy volunteers (HV), assessed using an unpaired samples Student’s t-test.
SE, Standard error; CI, Confidence interval; OS, Left eye; OD, Right eye.
*p < 0.05; **p < 0.01; ***p < 0.001.