Table 1.
Population baseline characteristics.
| Variable | All pregnancies | Ectopic pregnancy | Eutopic pregnancy | p value |
|---|---|---|---|---|
| Procedures | 7352 | 132 (1.80%) | 7220 (98.20%) | |
| Fresh ET | 4506 (61.29%) | 87 (65.91%) | 4419 (61.20%) | |
| Frozen ET | 2254 (30.66%) | 32 (24.24%) | 2222 (30.78%) | |
| Frozen oocytes | 206 (2.80%) | 3 (2.27%) | 203 (2.81%) | |
| IUI | 386 (5.25%) | 10 (7.58%) | 376 (5.21%) | |
| Female age (years) | 35.65 ± 3.85 | 35.86 ± 3.77 | 35.65 ± 3.86 | 0.516 |
| Female BMI (kg/m2) | 21.45 (19.72–23.74) | 21.48 (20.13–23.44) | 21.45 (19.72–23.74) | 0.798 |
| Smoking (%) | 2799 (38.07%) | 56 (42.42%) | 2743 (37.99%) | 0.299 |
| Infertility duration (years) | 3.67 (2.50–5.42) | 3.88 (2.58–5.58) | 3.58 (2.50–5.42) | 0.581 |
| Primary infertility | 3953 (53.77%) | 46 (34.85%) | 3907 (54.11%) | < 0.001 |
| Previous EP | 344 (4.68%) | 4 (3.03%) | 340 (4.71%) | 0.365 |
| Recurrent abortions | 19 (0.26%) | 0 (0.00%) | 19 (0.26%) | 0.555 |
| Basal FSH (mUI/mL) | 6.80 (5.50–8.30) | 6.30 (5.25–7.60) | 6.80 (5.50–6.80) | 0.011 |
| AMH | 2.20 (1.20–3.87) | 2.00 (1.12–3.31) | 2.20 (1.20–3.90) | 0.099 |
| AFC | 10 (6–17) | 10 (6–15) | 10 (6–17) | 0.334 |
| Positive history for pelvic adhesionsa | 961 (13.07%) | 33 (25.00%) | 928 (12.85%) | < 0.001 |
| Uterine fibroids | 1144 (15.46%) | 28 (21.21%) | 1116 (15.46%) | 0.071 |
| Indication to treatment | ||||
| Male factor | 3044 (41.40%) | 44 (33.33%) | 3000 (41.55%) | 0.057 |
| Tubal factor | 941 (12.80%) | 22 (16.67%) | 919 (12.73%) | 0.180 |
| Endometriosis | 319 (4.34%) | 11 (8.33%) | 308 (4.27%) | 0.031 |
| Unexplained | 950 (12.92%) | 19 (14.99%) | 931 (12.89%) | 0.611 |
| Male and female factor | 987 (13.42%) | 16 (12.12%) | 971 (13.45%) | 0.658 |
| Ovulation disorder | 225 (3.06%) | 4 (3.03%) | 221 (3.06%) | 1.000 |
| Diminished ovarian reserve | 659 (8.96%) | 11 (8.33%) | 648 (8.98%) | 1.000 |
| Multiple female factorsb | 227 (3.07%) | 5 (3.79%) | 222 (3.07%) | 0.606 |
BMI: body mass index; FSH: follicular stimulating hormone; AMH: anti Müllerian hormone; AFC: antral follicular count; ET: embryo transfer.
ai.e. pelvic infections, endometriosis, pelvic adhesions and frozen pelvis.
bMore than one female factor, including genetic or recurrent pregnancy failures.