Table 4.
Univariable and Multivariable logistic regression (EP vs Eutopic pregnancy) in IVF/ICSI.
| Variable | Fresh embryo transfer | Frozen embryo transfer | ||||||
|---|---|---|---|---|---|---|---|---|
| Univariable | Multivariable | Univariable | Multivariable | |||||
| OR (95% CI) | p value | OR (95% CI) | p value | OR (95% CI) | p value | OR (95% CI) | p value | |
| Female age | 1.04 (0.99–1.11) | 0.134 | 1.07 (1.01–1.13) | 0.033 | 0.95 (0.87–1.03) | 0.226 | ||
| BMI | 0.98 (0.92–1.04) | 0.477 | 0.96 (0.85–1.07) | 0.421 | ||||
| Smoking | 1.06 (0.69–1.64) | 0.783 | 1.31 (0.67–2.56) | 0.433 | ||||
| Years of infertility | 1.00 (0.99–1.02) | 0.785 | 0.95 (0.83–1.10) | 0.515 | ||||
| Primary infertility | 0.42 (0.27–0.66) | < 0.001 | 0.61 (0.31–1.21) | 0.157 | ||||
| Previous ectopic pregnancies | 0.54 (0.13–2.23) | 0.398 | 0.89 (0.21–3.76) | 0.878 | ||||
| Basal FSH (mUI/mL) | 0.88 (0.80–0.96) | 0.005 | 0.87 (0.79–0.96) | 0.003 | 0.96 (0.82–1.12) | 0.598 | ||
| Basal AMH | 1.01 (0.90–1.14) | 0.820 | 0.77 (0.62–0.96) | 0.022 | 0.81 (0.65–1.00) | 0.048 | ||
| AFC | 0.98 (0.95–1.02) | 0.336 | 0.97 (0.91–1.04) | 0.413 | ||||
| Positive history for pelvic adhesionsa | 2.35 (1.45–3.81) | 0.001 | 2.49 (1.53–4.07) | < 0.001 | 2.21 (1.02–4.75) | 0.043 | − | |
| Presence of myoma/s | 1.53 (0.91–2.55) | 0.108 | − | 1.28 (0.55–2.94) | 0.566 | |||
| Indication to treatment | ||||||||
| Male factor | 0.71 (0.45–1.11) | 0.128 | − | 0.79 (0.40–1.57) | 0.503 | |||
| Tubal factor | 1.44 (0.82–2.53) | 0.206 | 1.55 (0.67–3.59) | 0.301 | ||||
| Unexplained | 1.00 (0.50–2.00) | 0.990 | 0.97 (0.34–2.78) | 0.959 | ||||
| Endometriosis | 1.55 (0.67–3.61) | 0.304 | 3.03 (1.05–8.76) | 0.040 | − | |||
| Male and female factor | 0.96 (0.52–1.77) | 0.889 | 0.81 (0.28–2.30) | 0.690 | ||||
| Ovulation disorder | 0.65 (0.09–4.71) | 0.667 | 0.98 (0.13–7.22) | 0.980 | ||||
| Diminished ovarian reserve | 1.09 (0.58–2.07) | 0.781 | NC | |||||
| Multiple female factors | 1.57 (0.57–4.33) | 0.388 | 0.98 (0.13–7.22) | 0.980 | ||||
| Oocytes retrieved | 1.01 (0.97–1.05) | 0.703 | ||||||
| Embryos transferred | 0.85 (0.59–1.22) | 0.376 | 1.64 (0.99–2.70) | 0.051 | − | |||
| Blastocyst stage transferred embryo | 1.34 (1.03–1.74) | 0.030 | 1.32 (1.01–1.72) | 0.043 | 0.72 (0.49–1.05) | 0.089 | − | |
| Difficult transfers | 1.82 (1.16–2.85) | 0.009 | 1.86 (1.18–2.93) | 0.007 | 0.72 (0.28–1.87) | 0.503 | ||
A minus symbol in multivariable column indicates a variable entered in the analysis and then removed for lack of significance. Multivariable results are corrected by years.
BMI: body mass index; FSH: follicular stimulating hormone; AMH: anti Müllerian hormone; AFC: antral follicular count; ET: embryo transfer.
Significant values are in bold.
ai.e. pelvic infections, endometriosis, pelvic adhesions and frozen pelvis.