FIG. 2.

Production of TNF-α (●) and IL-6 (■) by RAW 264.7 cells incubated for 6 h with the indicated doses of S. aureus LTA in the absence (solid line) or presence (broken line) of 20 μg of CEMA. TNF-α and IL-6 concentrations in the cell supernatant were determined by ELISA. The levels of TNF-α and IL-6 produced by macrophages incubated in medium alone for 6 h were less than 0.3 ng/ml. The experiment was repeated three times with similar results, and the data from one representative experiment are shown.