TABLE 2.

Activity of cationic antimicrobial peptides against gram-positive bacteria and E. coli^a

Strain	MIC (μg/ml)b
	CP26	CEME	CEMA	CP29	CP203	CP207	CP208	CM5	CM7	CPα2	PBc
S. aureus
RN4220	64	4	4	8	8	16	>64	64	4	16	32
25923	>64	8	8	16	16	32	>64	>64	16	16	32
SAP0017 (MRSAe)	64	4	4	16	8	16	>64	>64	8	16	32
Clinical isolate	>64	8	16	16	8	16	>64	>64	16	16	16
Clinical isolate	>64	4	16	16	8	16	>64	>64	16	32	16
S. epidermidis	16	4	4	8	4	8	>64	32	8	16	16
S. pyogenes 19615	16	8	8	8	4	8	>64	16	8	16	8
E. faecalis 29212	>64	32	32	64	32	64	>64	>64	16	64	>64
B. subtilis	32	8	8	8	16	16	>64	64	8	16	64
L. monocytogenes	32	4	4	4	4	8	64	64	4	8	4
C. xerosis	2	4	4	4	2	2	32	4	4	4	2
E. coli UB1005d	1	2	2	2	2	2	32	5	2	2	0.5

^aBacterial strains were cultured with serial twofold dilutions of the various peptides (0.5 to 64 μg/ml) for 18 h as described in Materials and Methods. 

^bThe MIC represents the minimal concentration of peptide that completely inhibited growth. The values represent the averages of data from three experiments. 

^cPB, polymyxin B. 

^dMICs for this organism were taken from reference 22. 

^eMRSA, methicillin-resistant S. aureus.