Table 2.
Rehospitalizations during the 12-month follow-up period after initial admission for transplantation
| Allo-HSCT | SOT | |||||||
|---|---|---|---|---|---|---|---|---|
| All patients n = 226 PYs = 174.9 |
CMV n = 66 PYs = 51.9 |
No CMV n = 160 PYs = 122.9 |
p value | All patients n = 250 PYs = 231.0 |
CMV n = 42 PYs = 39.5 |
No CMV n = 208 PYs = 191.5 |
p value | |
| Patients with a rehospitalization, n (%) | 182 (80.5) | 60 (90.9) | 122 (76.3) | 0.004 | 208 (83.2) | 38 (90.5) | 170 (81.7) | 0.121 |
| Number of all-cause rehospitalizations, n | 650 | 232 | 418 | – | 708 | 143 | 565 | – |
|
LOS (all-cause) in days, mean (SD) | median |
17.9 (28.0) | 4.5 | 22.4 (33.0) | 8 | 15.4 (24.5) | 3 | < 0.001 | 8.4 (16.3) | 3 | 11.6 (16.1) | 6 | 7.5 (16.2) | 3 | 0.003 |
| Number of CMV-related rehospitalizationsb, n | – | 61 | – | – | – | 41 | – | – |
|
LOS (CMV-related)b in days, mean (SD) | median |
– | 39.3 (42.1) | 23 | – | – | – | 23.0 (19.1) | 20 | – | – |
|
Number of all-cause rehospitalizations, ppy (95% CI) |
3.7 (3.2–4.3) | 4.5 (3.7–5.3) | 3.4 (2.7–4.1) | 0.050 | 3.1 (2.7–3.4) | 3.6 (2.9–4.4) | 3.0 (2.6–3.3) | 0.116 |
|
Total all-cause rehospitalization days, ppy (95% CI) |
62.4 (52.2–72.7) | 93.3 (70.1–116.6) | 49.4 (39.3–59.4) | 0.001 | 24.3 (20.1–28.6) | 42.0 (27.4–56.5) | 20.7 (16.7–24.7) | 0.005 |
|
Total all-cause hospitalization daysa, ppy (95% CI) |
117.8 (106.0–129.5) | 150.6 (125.1–176.1) | 103.9 (91.8–116.0) | 0.001 | 73.9 (64.8–83.0) | 88.6 (69.7–107.6) | 70.9 (60.7–81.1) | 0.101 |
Allo-HSCT allogeneic hematopoietic stem cell transplantation, CI confidence interval, CMV cytomegalovirus, LOS length of stay, PY patient year, ppy per patient-year, SD standard deviation, SOT solid organ transplantation
aTotal hospitalization days during the 12 months post-index period including days spent at the hospital during the index admission for transplantation
bCMV-related defined as rehospitalizations with CMV as main or primary diagnosis