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. 2022 Jun 15;32(12):8238–8246. doi: 10.1007/s00330-022-08909-x

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 2 — Sensitivity with 95% confidence interval (CI) for scenarios 1–11. The vertical dotted line with 95% CI bands represents the sensitivity after independent double reading where interval cancers (IC) are defined to be false negatives. In (a) only screen-detected cancers (SDC) are included as true positives and in (b) IC with prior screening examination selected for consensus were included in addition to SDC. Reduction in screen-reading volume for the different scenarios is presented to the right