Table 1.

Definition of different scenarios artificial intelligence (AI) and radiologists can be combined and used in screen-reading. Percentage of screen-readings performed by AI, by the radiologists (R1 and R2) and the corresponding reduction in screen-reading volume are also presented. The volume reduction relates to the screen-reading of mammograms prior to consensus and further assessments. An AI score of 1 indicates the lowest probability of malignancy by the AI system, and 10 indicates the highest probability

Scenarios		Selection rate of AI and radiologists/setup based on AI score	AI, % of screen-readings	R1, % of screen-readings	R2, % of screen-readings	Reduced screening volume, %
	Standard independent double reading	0	0	100	100	0
1	AI as one of two readers	AI and R1 selects 5.8% each*	100	100	0	50
2	AI as one of two readers	AI selects 10.1% (AI score = 10) and R1 selects 5.8%*	100	100	0	50
3	AI selects cases to be double read	AI score 1–5: negative AI score 6–10: R1+R2	100	50	50	50
4	AI selects cases to be double read	AI score 1–7: negative AI score 8–10: R1+R2	100	30	30	70
5	AI selects cases to be double read	AI score 1–9: negative AI score 10: R1+R2	100	10	10	90
6	AI selects cases to be single read	AI score 1–5: negative AI score 6–10: R1	100	50	0	75
7	AI selects cases to be single and double read	AI score 1–5: R1 AI score 6–10: R1+R2	100	100	50	25
8	AI selects cases to be single and double read	AI score 1–7: R1 AI score 8–10: R1+R2	100	100	30	35
9	AI selects cases to be single and double read	AI score 1–5: negative AI score 6–7.5: R1 AI score 7.6–10: R1+R2	100	50	25	63
10	AI selects cases to be single and double read	AI score 1–5: negative AI score 6–7.5: R1+R2 AI score 7.6–10: R1	100	50	25	63
11	AI selects cases to be recalled	3.2%*	100	0	0	100

*5.8% mimics the average selection rate/positive interpretations of the individual radiologists in the study sample, and 3.2% mimics the recall rate in the study sample after independent double reading