Table 1.

Prediction of rRNA transcription machineries in Giardia duodenalis and Cryptosporidium parvum

Homo sapiens			Saccharomyces cerevisiae			Gardia duodenalis (Assemblage A_isolate_WB)					Cryptosporidium parvum (Iowa II)
Gene	UniProtKBa	Sizeb	Gene	UniProtKBa	Sizeb	Gene	UniProtKBa	Sizeb	E-value	Ic	Gene	UniProtKBa	Sizeb	E-value	Ic
TBP-TAF complex SL1
TBP	P62380	339	TBP	P13393	240	GL50803_1721	E2RU70	200	6e−05	25	cgd8_2030 cgd8_210	Q6SEL4 Q5CPZ4	249 195	4e−67 7e−14	51 32
TAF1C	Q15572	869	Rrn6	P32786	894	–	–	–	–	–	–	–	–	–	–
TAF1B	Q53T94	588	Rrn7	P40992	514	–	–	–	–	–	–	–	–	–	–
TAF1A	Q15573	450	Rrn11	Q04712	507	–	–	–	–	–	–	–	–	–	–
TAF1D	Q9H5J8	278	–	–	–	–	–	–	–	–	–	–	–	–	–
TAF12	Q16514	161	–	–	–	–	–	–	–	–	–	–	–	–	–
RRN3	Q9NYV6	651	Rrn3	P36070	627	GL50803_11742	A8B8V3	556	2e−05	23	cgd6_2810	Q5CX25	882	1e−04	27
Transcription activator UBF
UBF	P17480	764	UAF30	Q08747	228	GL50803_17626 GL50803_3349	A8BW36 A8BDD1	204 183	1e−05 5e−05	30 30	–	–	–	–	–
			Rrn5	Q02983	363						–	–	–	–	–
			Rrn9	P53437	365						–	–	–	–	–
			Rrn10	P38204	145						–	–	–	–	–
RNA polymerase I complex
POLR1A	O95602	1720	A190	P10964	1664	GL50803_16223 GL50803_23496 GL50803_89347	A8B4F1 A8B7R7 E2RTQ5	1741 2142 2076	1e−78 3e−70 7e−36	28 28 26	cgd3_2620 cgd6_3290 cgd5_730	Q5CUJ2 Q5CWY0 A3FQH3	1895 1871 1805	9e−109 2e−102 1e−70	35 35 33
POLR1B	Q9H9Y6	1135	A135	P22138	1203	GL50803_29436 GL50803_17187 GL50803_17448	A8B827 A8B2N4 E2RU19	1235 1238 1293	3e−129 3e−102 4e−83	34 30 28	cgd1_2770 cgd7_3720 cgd8_170	Q5CSG7 Q5CY45 Q5CPZ8	1281 1177 1287	3e−122 3e−122 5e−121	36 29 29
POLR1C	O15160	346	AC40	P07703	335	GL50803_10055 GL50803_7474	A8B9C8 E2RTY7	350 326	5e−47 5e−16	33 28	cgd8_300 cgd1_2710	Q5CPY6 Q5CSH3	344 355	5e−69 5e−29	40 29
POLR1D	P0DPB6	133	AC19	P28000	142	GL50803_10840	A8B7A8	101	1e−15	59	cgd4_3200	A3FQL8	98	4e−15	60
POLR1E	Q9GZS1	414	A49	Q01080	415	–	–	–	–	–	–	–	–	–	–
POLR1F	Q3B726	338	A43	P46669	326	GL50803_17422	A8BD91	229	1e−03	24	cgd1_1620	Q5CSR5	256	7e−07	27
POLR1G	O15446	510	A34.5	P47006	233	–	–	–	–	–	–	–	–	–	–
POLR1H	Q9P1U0	126	A12.2	P32529	125	GL50803_8518	A8BBB2	103	2e−12	41	cgd7_503 cgd3_2550	F0X620	106 246	7e−08 3e−05	27 41
POLR2E	P19388	210	Rpb5	P20434	215	GL50803_137609 GL50803_8157	E2RU58 E2RU93	229 201	7e−26 5e−16	32 26	cgd2_980	Q5CTZ0	205	7e−62	45
POLR2F	P61218	127	Rpb6	P20435	155	GL50803_15955	E2RTN0	104	4e−26	52	cgd7_4770	Q5CXV6	129	4e−36	72
POLR2H	P52434	150	Rpb8	P20436	146	GL50803_15144	E2RU32	150	1e−07	27	cgd1_2260	Q5CSK9	144	3e−22	35
POLR2K	P53803	58	Rpb12	P40422	70	GL50803_9509	E2RU91	54	1e−04	33	cgd7_3240	A3FPP8	71	9e−12	43
POLR2L	P62875	67	Rpb10	P22139	70	GL50803_14413	A8BAL6	122	1e−22	59	cgd4_3260	A3FQL9	72	1e−28	66
RPA3	P35244	121	RPA14	P50106	137	–	–	–	–	–	–	–	–	–	–

^aAccess number in the UniProt Knowledgebase

^bNumber of amino acids

^cI (Identity) values expressed in percentage (%)