FIGURE 3.

The lipid storage function of adipose tissue in ob/ob mice was retained by ponatinib (A) The visceral white adipose tissue of ob/ob mice in ponatinib group or vehicle group. n = 5. Scale bar, 5 mm. (B) Weight of visceral white adipose tissue of ob/ob mice treated with or without ponatinib. n = 5. (C) Representative images of HE staining of visceral white adipose tissue of ob/ob mice in ponatinib group or vehicle group. n = 5. Scale bar, 100 μm and 200 μm. (D) Analyzation of adipocyte size in (C) n = 5. Statistical comparisons were performed with unpaired two-tailed Student’s t-test (B–D). Data represent mean ± SEM. ^# p < 0.05, ^### p < 0.001vs. ob/ob + vehicle.