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. 2022 Nov 15;13:1041099. doi: 10.3389/fneur.2022.1041099

Figure 1.

Figure 1

BSCB leakage of intravenously injected fluorescence-dextran in the injured segment after SCI. (A) Representative images of in vivo two-photon microscopy of the intravenously injected 40 kDa TRITC-dextran leaking from the disrupted BSCB an hour post-SCI. The 40 kDa TRITC-dextran did not leak from the normal BSCB pre-SCI. Scale bar: 200 μm. (B) The effect of TH on the volume of extravascular TRITC-dextran leaked from the disrupted BSCB an hour post-SCI (P = 0.997). (C) The effect of TH on the integrated intensity of the extravascular TRITC-dextran leaked from the disrupted BSCB with TH an hour post-SCI (P = 0.688). NT, normothermia; TH, therapeutic hypothermia; ns, non-significance. n = 6 mice per group, data are shown as mean ± SEM; nested, two-way ANOVA.