TABLE 3.

Description of main and secondary variables.

Primary outcome Postoperative NRS score (0–10). 0 means absence of pain and 10 is the severest pain imaginable. Postoperative NRS score was recorded every half an hour for the first hour, every hour for the next 2 h, and every 4 h for the next 24 h. Secondary outcomes Range of nalbuphine requirements 0: no use 1: <10 mg/day 2: 10–20 mg/day 3: More than 20 mg/day PONV, incidence and severity of PONV NRS: A 10 cm ruler was used as the scale. One end of the scale was 0, indicating no nausea and vomiting, and the other end was 10, indicating the severest unbearable nausea and vomiting (1–4 as mild, 5–6 as moderate, 7–10 as severe). Need for rescue antiemetic medication 1: Yes 2: No L-SRS The surgeon will score the quality of the intra-abdominal conditions at 15 min intervals using the L-SRS [see Martini et al. (22) and Boon et al. (23)]. In brief, the L-SRS is a 5-point Likert scale that enables the quantification of surgical conditions in a standardized fashion. The scale runs from 1 to 5: extremely poor (score = 1), poor (=2), acceptable (=3), good (=4), and excellent (=5) surgical working conditions. Postoperative agitation Riker Sedation-Agitation Scale (SAS) (Table 4) Postoperative chills Wrench classification: Grade 0, no chills; Grade 1, bundles and/or peripheral vasoconstriction and/or peripheral cyanosis, but no fibrillation; Grade 2, PACU stay time EuroQol five-dimensional questionnaire (EQ-5D) The EQ-5D descriptive system is a preference-based HRQL measure with one question for each of the five dimensions that include mobility, self-care, usual activities, pain/discomfort, and anxiety/depression. Length of hospital stay (days) Intraoperative awareness 1: Yes 2: No Hemodynamically unstable treatments