Table 4.

Kruskal-Wallis H tests and LEfSe analysis identification of associations between pre-menopausal and post-menopausal women.

Taxon name	Taxon rank	LDA effect size	p-value	PRE (%)	POST (%)
Lactobacillales	Order	5.34	0.01	74.34	31.84
Bacilli	Class	5.32	0.01	74.68	34.27
Lactobacillaceae	Family	5.31	0.03	65.87	24.69
Lactobacillus	Genus	5.29	0.04	63.16	23.73
Firmicutes	Phylum	5.23	0.01	77.84	46.10
Proteobacteria	Phylum	4.94	0.00	0.82	18.65
Gammaproteobacteria	Class	4.92	0.00	0.76	17.64
Enterobacterales	Order	4.68	0.00	0.42	9.82
Lactobacillus_uc	Species	4.54	0.03	9.72	2.62
Coriobacteriales	Order	4.51	0.01	0.76	6.94
Coriobacteriia	Class	4.51	0.01	0.76	6.94
Coriobacteriaceae	Family	4.51	0.01	0.76	6.94
Atopobium	Genus	4.50	0.01	0.45	6.43
Pseudomonadales	Order	4.45	0.01	0.31	6.38
Bacteroidetes	Phylum	4.44	0.02	2.36	8.03
Atopobium vaginae	Species	4.44	0.01	0.27	5.50
Pseudomonadaceae	Family	4.43	0.03	0.29	6.13
Pseudomonas	Genus	4.42	0.03	0.29	6.00
Prevotellaceae	Family	4.38	0.05	2.24	7.31
Morganellaceae	Family	4.37	0.00	0.00	4.38
Proteus	Genus	4.36	0.01	0.00	4.26
Tissierellia	Class	4.36	0.00	1.92	6.54
Tissierellales	Order	4.36	0.00	1.92	6.54
Peptoniphilaceae	Family	4.36	0.00	1.92	6.54
Prevotella	Genus	4.34	0.05	2.22	6.87
Enterobacteriaceae	Family	4.31	0.02	0.38	4.58
Proteus vulgaris group	Species	4.31	0.01	0.00	3.83
Escherichia	Genus	4.30	0.04	0.37	4.43
Escherichia coli group	Species	4.26	0.04	0.33	4.03
Clostridia	Class	4.08	0.01	0.46	2.98
Clostridiales	Order	4.08	0.01	0.46	2.98
Bacillales	Order	4.04	0.02	0.29	2.42
Lactobacillaceae_uc	Genus	4.00	0.02	2.70	0.71

Only those with p < 0.05 and linear discriminant analysis (LDA) effect size > 4 are presented.

% refers to the percentage of distribution occupied by each group.

PRE, pre-menopause group; POST, post-menopause group.