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. 2020 Dec 31;31(2):226–232. doi: 10.4014/jmb.2008.08048

Fig. 1. SFTSV NSs is a potent IFN antagonist.

Fig. 1

(A) HEK293T cells were transfected with SFTSV NSs-myc tagged plasmid. SFTSV NSs was detected by rabbit anti-myc tag antibody (red) and nucleus was stained with DAPI (blue). Scale bar, 10 μm. (B) Luciferase reporter assay of HEK293T cells transfected with IFN-β, ISRE, IP-10 and IFN-λ1 luciferase reporters together with RIG-I or TBK1 along with empty vector or increasing amount of SFTSV-NSs. Each error bar shows the means ± standard deviations of three independent experiments. p < 0.05; **p < 0.01; ***p < 0.001 versus empty vector-transfected cells.