Table 2.
vacA genotypes and vacuolating toxin activity of H. pylori isolates recovered from patients with chronic gastritis, peptic ulcer, or gastric cancer.
| vacA genotypes and Vac activity | Total (n=116) | Chronic gastritis (n=38) | Peptic ulcer (n=39) | Gastric cancer (n=39) |
|---|---|---|---|---|
| s1 | 116(100%) | 38(100%) | 39(100%) | 39(100%) |
| s1a | 37 (32%) | 18 (47%) | 11 (28%) | 8 (21%) |
| s1b | 0 | 0 | 0 | 0 |
| s1c | 79 (68%) | 20 (53%) | 28 (72%)a | 31 (79%) b |
| s2 | 0 | 0 | 0 | 0 |
| m1 | 109 (94%) | 36 (95%) | 37 (95%) | 36 (92%) |
| m2 | 7 (6%) | 2 (5%) | 2 (5%) | 3 (8%) |
| i1 | 110 (95%) | 35 (89%) | 38 (97%) | 37 (95%) |
| i2 | 3 (2.5%) | 1 (3%) | 0 | 2 (5%) |
| i1,i2(-) | 3 (2.5%) | 2 (5%) | 1 (3%) | 0 |
| Vacuolating toxin activity | 21.8±19.2 | 20.3±17.2 | 18.7±18.0 | 26.3±21.2 |
ap = 0.103 and bp = 0.017 compared with that in chronic gastritis with Fisher’s exact test.