Fig. 2. Si-circ_0001947#2 intensified cell proliferation, induced cell cycle arrest at S phase and restrained apoptosis, while overexpressed circ_0001947 did the opposite.
A-B. Apoptosis of NSCLC cells transfected with sicirc_ 0001947#2 or overexpressed circ_0001947 was analyzed by flow cytometry. (***p < 0.001 vs. si-NC group; ^^^p < 0.001 vs. NC group) C-D. Proliferation of NSCLC cells transfected with si-circ_0001947#2 or overexpressed circ_0001947 was analyzed by colony formation assay. (***p < 0.001 vs. si-NC group; ^^p < 0.01 vs. NC group) E-F. Cell cycle of NSCLC cells transfected with si-circ_0001947#2 or overexpressed circ_0001947 was analyzed by flow cytometry. (**p < 0.01 vs. si-NC group; ^p < 0.05, ^^p < 0.01 vs. NC group)