Fig. 7. DOK7 was down-expressed in NSCLC tissues and cells, whose expression was regulated by circ_0001947.
A. The level of DOK7 in 40 NSCLC tissues and adjacent non-tumor tissues was analyzed by qRT-PCR. GAPDH was used as the internal control. (&&&p < 0.001 vs. normal) B. The level of DOK7 in NSCLC cells and normal cells was analyzed by qRT-PCR. GAPDH was used as the internal control. (###p < 0.001 vs.16HBE) C. The effects of circ_0001947 knockdown and miR-661 I on DOK7 expression were analyzed by qRT-PCR. GAPDH was used as the internal control. (***p < 0.001 vs. si-NC + IC group; ‡‡‡ p < 0.001 vs. si-NC + I group; △△△ p < 0.001 vs. si-circ_0001947#2 + IC group) D. The effects of circ_0001947 overexpression and miR-661 M on DOK7 expression were analyzed by qRT-PCR. GAPDH was used as the internal control. (^^p < 0.01, ^^^P<0.001 vs. NC + MC group; ΦΦΦp < 0.001 vs. circ_0001947 + MC group; †††p < 0 .001 vs. NC + M group)
