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. 2022 Nov 15;13:1070043. doi: 10.3389/fimmu.2022.1070043

Table 3.

Univariable Cox regression analysis after the LASSO regression analysis, without tumor invasion locations.

Variables N HR 95% CI p
BMI 0.214
<25 161
≥25 138 0.723 [0.434,1.206]
T category 0.002
Ta 181 1 (reference)
T1 118 2.206 [1.332,3.652]
Prior recurrence status <0.001
Primary 264 1 (reference)
Recurrent 35 3.369 [1.941,5.847]
Tumor number 0.016
Single 146 1 (reference)
Multiple 153 1.911 [1.127,3.241]
Gross hematuria 0.171
No 60 1 (reference)
Yes 239 1.682 [0.800,3.538]
Times of IVI <0.001
0-1 36 1 (reference)
2-12 56 0.534 [0.296,0.961] 0.036
>12 207 0.081 [0.043,0.152] <0.001
SII 0.003
<525.26 215 1(reference)
≥525.26 84 2.17 [1.308,3.599]

HR, hazard ratio; CI, confidence interval; BMI, body mass index, weight/height2; IVI,intravesical instillation; PLR, platelet-lymphocyte ratio; SII, systemic immune-inflammation index,platelet* neutrophil/lymphocyte; De Ritis ratio, aspartate transaminase/alanine transaminase. Bolded p-values indicate statistically significant correlations (p < 0.05).