TABLE 1.

Clinical characteristics of patients with meningococcal disease (n = 40) and characterization of associated strains

Patient group and no.a	Meningococcal strain	Approx MW (103)b		Disease categoryc	Preadmission symptoms (h)	Intermediate sampling day
		TbpA	TbpB
I (n = 8)
1	B:15P1.7,16	NT	NT	2	12	15
2	B:15P1.7,16	98	83	1	12	17
3	B:15P1.7,16	NT	NT	1	18	16
4 (V−A+C[1])	B:15P1.7,16	NT	NT	3	20	12
5	B:15P1.7,16	95	ND	4	11	16
6	B:15P1.7,16	98	81	1	25	10
7	B:15P1.7,16	NT	NT	4	24	16
8	B:15P1.7,16	98	83	2	10	17
II (n = 7)
9	C:15P1.7,16	98	83	4	20
10	C:15P1.7,16	98	83	3	20	24
11	C:15P1.7,16	95	ND	4	48	17
12	C:15P1.7,16	98	83	1	16	8
13	C:15P1.7,16	98	83	1	24	5
14	C:15P1.7,16	98	81	2	16	7
15	C:15P1.7,16	NT	NT	3	30	4
III (n = 10)
16	B:15:P1.2	98	85	3	23	9
17	B:15:P1.2,5	98	85	4	36	5
18	B:15:P1.12,13	NT	NT	2	12	24
19	B:15:P1.12,13	NT	NT	2	11	15
20	B:15:P1.12	98	85	4	24	18
21	B:15:P1.12	NT	NT	4	18	5
22 (V−B [3])	B:15:P1.12	98	83	1	14	13
23 (V−B [3])	B:15:P1.12	98	83	3	18	15
24 (V−B [3])	B:15:P1.12	NT	NT	1	14	10
25 (V−B [1])	B:15:P1.12	NT	NT	1	26	3
IV (n = 6)
26	C:2a:P1.2	95	64	4	20	6
27	C:2a:P1.2	98	68	2	11	13
28	C:2a:P1.2	98	68	4	11	14
29	C:2a:P1.2	98	85	2	28	4
30 (V−B [4]	C:2a:P1.2	NT	NT	2	20	15
31 (V−B [4]	C:2a:P1.2	98	68	2	10	17
V (n = 9)
32	B:NT:P1.12	95	85	4	18	13
33	B:NT:P1.16	98	85	1	24	18
34	B:NT:P1.3	NT	NT	4	20	8
35	B:NT:NT	98	83	3	30	14
36	B:4:NT	98	ND	4	10	16
37	B:4:P1.12	98	85	2	25	16
38	B:8:P1.15	98	83	1	18	16
39	B:19:P1.15	98	85	4	16	8
40	Microscopyd	NT	NT	3	11	14

^aV−A+C, immunized with meningococcal polysaccharide A+C vaccine; V−B, immunized with meningococcal serogroup B OMV vaccine. Numbers in brackets indicate years since vaccination. 

^bND, not determined, band not detected; NT, not tested. 

^c1, meningitis; 2, septicemia with shock; 3, meningitis and septicemia with shock; 4, septicemia without septic shock and with or without meningitis. 

^dGram-negative diplococci in cerebrospinal fluid.