Table 4.

Patients with negative ACSS questionnaire result and positive urinary test(s) result but most probable diagnosis AC-positive (false-negative ACSS)

Patient number	Age (yrs)	ACSS form A result a	Total score typical symptoms b, f	Total score differential symptoms d, f	Total score QoL e, f	ACSS form B result g	Urinary test(s) result h	most probable diagnosis k	Argumentation for ACSS false-negative
003	70	0	4	0	5	0	1	1	Clear growth dipslide (10^7), scores QoL discomfort and daily activities moderate; probably symptoms rated too low
016	23	0	5	2	1	1	1	1	Moderate scores for frequency, abdominal pain, flank pain, mild for incomplete emptying of the bladder; probably symptoms rated too low.
041	47	0	3	2	3	2	1	1	Clear growth dipslide (10^5), ACSS form B: most symptoms still present; probably symptoms rated too low
043	63	0	2	1	1	1	1	1	Patient recognises AUC by urine scent and goosebumps from bladder to head when urinating

^a Result ACSS questionnaire based on total typical symptoms score ≥ 6:1 = AC-positive; 0 = AC-negative.

^b Total typical symptoms score: frequency + urgency + burning pain when urinating + incomplete emptying of the bladder + abdominal pain + blood seen in urine.

^d Total differential symptoms score: loin pain + vaginal discharge + urethral discharge + high body temperature + temperature specified.

^e Total QoL score: general discomfort + influence on work/ daily activities + influence on social activities.

^f severity score per symptom/ item: 0 = absent, 1 = mild, 2 = moderate, 3 = severe.

^g ACSS B: treatment result: 0 = all symptoms have gone away; 1 = majority of symptoms have gone away; 2 = majority of symptoms is still present; 3 = no changes in my symptoms; 4 = my condition is worse.

^h Urinary test result: dipstick and eventual dipslide: 1 = AC-positive; 0 = AC-negative.

^k most probable diagnosis, based on evaluation with independent GP: 1 = AC-positive; 0 = AC-negative.