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. 2022 Nov 28;80(1):18–29. doi: 10.1001/jamaneurol.2022.4166

Table 3. Propensity Score–Matched Generalized Estimating Equation Model for Clinical Outcomes Within 24 Months After Permanent Spinal Cord Stimulator Placement vs Conventional Medical Management.

Outcome Follow-up, mo Odds ratio (95% CI)
Chronic opioid use 1-12 1.14 (1.01-1.29)
13-24 1.06 (0.94-1.20)
Long-acting opioid use 1-12 1.28 (1.11-1.49)
13-24 1.16 (0.99-1.36)
High MME 1-12 1.81 (1.60-2.04)
13-24 1.04 (0.92-1.18)
Epidural and facet corticosteroid injections 1-12 0.44 (0.39-0.51)
13-24 1.00 (0.87-1.14)
Radiofrequency ablation 1-12 0.57 (0.44-0.72)
13-24 0.84 (0.66-1.09)
Advanced imaging 1-12 0.84 (0.74-0.96)
13-24 0.97 (0.85-1.11)
Spine surgery 1-12 0.72 (0.61-0.85)
13-24 0.91 (0.75-1.09)
NSAIDs 1-12 0.95 (0.83-1.07)
13-24 0.99 (0.87-1.13)
Muscle relaxants 1-12 1.13 (0.99-1.28)
13-24 1.03 (0.91-1.17)
Systemic steroids 1-12 0.94 (0.83-1.07)
13-24 1.09 (0.97-1.24)
TCA/SNRI antidepressants 1-12 1.05 (0.92-1.20)
13-24 1.16 (1.02-1.32)
Gabapentinoids 1-12 1.06 (0.94-1.20)
13-24 1.22 (1.08-1.37)
Benzodiazepines 1-12 1.01 (0.88-1.14)
13-24 0.87 (0.76-1.00)

Abbreviations: MME, morphine milligram equivalents; NSAID, nonsteroidal anti-inflammatory drug; SNRI, serotonin and norepinephrine reuptake inhibitor; TCA, tricyclic antidepressant.