Table 1:
Maternal and Child Characteristics
| Mean ± SD, or n (%) | 25% (Q1) | 75% (Q3) | IQR | |
|---|---|---|---|---|
|
| ||||
| Maternal Variables: | ||||
| Age (yrs) | 28.4 ± 4.7 | 26.0 | 31.0 | 5.0 |
| SES index | 3.22 ± 0.56 | 2.67 | 3.67 | 1.00 |
| Ethnicity, n (%Hispanic) | 12 (43%) | - | - | - |
| Allostatic Load Composite Score | 0.56 ± 4.08 | −2.59 | 2.55 | 5.14 |
| Pre-pregnancy BMI (kg/m2) | 28.9 ± 6.9 | 22.8 | 33.7 | 11.0 |
| Log HOMA-IR | 0.42 ± 0.22 | 0.28 | 0.56 | 0.28 |
| FFA (mean18) | 14.9 ± 3.7 | 12.2 | 17.3 | 5.1 |
| CRP (mg/L) | 10.4 ± 9.7 | 3.4 | 14.2 | 10.8 |
| IL-6 (pg/ml) | 1.03 ± 1.07 | 0.44 | 1.31 | 0.87 |
| Cortisol AUC (μg/dL) | 3.36 ± 1.31 | 2.83 | 3.71 | 0.88 |
| Blood Pressure (diastolic + systolic) | 172 ± 17 | 160 | 180 | 20 |
| Child Variables: | ||||
| Offspring Sex, n (%Male) | 16 (53%) | - | - | - |
| Offspring Age (yrs) | 4.5 ± 0.6 | 3.9 | 5.1 | 1.2 |
| Lymphocyte Count (thos/μL) | 3.27 ± 0.96 | 2.50 | 3.90 | 1.40 |
| Monocyte Count (thos/μL) | 0.50 ± 0.24 | 0.35 | 0.60 | 0.25 |
| Mitochondrial measures: | ||||
| Complex I (mmol/min/106 cells) | 9.78 ± 3.35 | 7.64 | 11.28 | 3.64 |
| Complex II (mmol/min/106 cells) | 64.7 ± 29.2 | 47.7 | 77.0 | 29.4 |
| Complex IV (mmol/min/106 cells) | 16.6 ± 6.2 | 12.3 | 20.4 | 8.1 |
| CS (mmol/min/106 cells) | 126.7 ± 41.7 | 96.3 | 141.2 | 44.8 |
| mtDNAcn (copies per cell) | 407.4 ± 112.5 | 317.2 | 467.6 | 150.4 |
The maternal allostatic load score and the components are mean pregnancy values (mean across early-, mid- and late- gestation visits). SES= socioeconomic status; BMI= body mass index; Log HOMA-IR= logarithmic base 10 of the homeostatic model of insulin resistance; FFA= free fatty acid; CRP= c-reactive protein; IL-6= interleukin 6; AUC= Area under the curve; CS= citrate synthase; mtDNAcn= mitochondrial DNA copy number; all reported enzymatic activity levels are normalized to nuclear DNA copies (i.e., per cell).