Figure 1.

Transcriptional and metabolic responses to lignin pathway perturbations. A, Scheme of the lignin biosynthetic pathway. The enzymes for which genes were targeted in this study are highlighted in red. The enzyme corresponding with the F5H gene from Selaginella moellendorffii is highlighted in blue. The blue panel in the top right shows a simplified scheme of the aliphatic glucosinolate biosynthetic pathway. B, Hierarchical clustering of DEGs from 13 lignin mutants compared with wild type. Gene ontology terms of biological processes for 16 clusters are shown on the right. Terms written in black are statistically significant (false discovery rate, FDR < 0.01) and those in gray indicate FDR between 0.01 and 0.1. This figure was modified from figure 7 from Wang et al. (2022). Subgroups highlighted in yellow: mutants with fewer DEGs; subgroups highlighted in red: mutants with more DEGs.