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. 2022 Nov 11;65(22):15416–15432. doi: 10.1021/acs.jmedchem.2c01357

Figure 9.

Figure 9

Interactions of the PepLites within the acetyl lysine pocket of ATAD2 and BRD4. (a) PLKAc (green, PDB: 7ZG2) overlaid with diacetylated histone peptide (cyan, PDB: 3UVX) and FL11 (yellow, PDB: 7ZAA) bound to BRD4; (b) PLA (gold, PDB: 7ZFV) and PLKAc (green, PDB: 7ZG2) bound to BRD4. (c) PLG, PLA, PLV bound to BRD4 (PDB: 7ZFY, 7ZFV, 7ZFZ) and PLA, PLV, PLI bound to ATAD2 (PDB: 7Z9I, 7Z9N, 7R05).