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. 2022 Nov 15;65(22):15300–15311. doi: 10.1021/acs.jmedchem.2c01273

Figure 4.

Figure 4

(A) Six residues in peptide 29 (X1–X6) were modified one at a time and replaced with one of the listed amino acids. (B) List of modified sequences with improved affinity for PRMT5-MEP50 over 29.